Show se uskutečnila 21. února 2010 ve Scottrade Center (St. Louis, Missouri). Na kartě se sešlo šest zápasů. 1) Sheamus vs. Triple H vs. John Cena vs. Randy Orton vs. Ted DiBiase vs. Kofi Kingston (WWE Championship, Elimination Chamber) 2) John Cena vs. Batista (WWE Championship) 3) Drew McIntyre vs. Kane (Intercontinental Championship) 4) LayCool vs. Gail Kim & Maryse 5) The Miz vs. MVP (United States Championship) 6) The Undertaker vs. CM Punk vs. Chris Jericho vs. John Morrison vs. Rey Mysterio vs. R-Truth (World Heavyweight Championship, Elimination Chamber) (TheSpearCZ)